Antimatter

Antimatter is a phenomenon that completely destroys matter within the multiverse, having the ability to completely destroy a universe.

History
Between 2018 and 2019, Jay Garrick detected a number of antimatter signatures throughout the multiverse.

Antimatter was unleashed upon Earth-2, killing its population and ultimately destroying the universe.

Possible future
In a potential future, a wave of antimatter made its way through Central City, destroying all of its citizens and, ultimately, the universe.

Behind the scenes

 * In the real world, antimatter is defined as the "antiparticles" of regular matter found in the universe. Particle accelerators around the world regularly produce tiny amounts, with only a few nanograms having been produced in total.