Amélie was the late Philippe's wife.
Starting a family
During the Anti-Monitor Crisis, Amélie as well as everyone in the multiverse except for the seven Paragons, was killed in an antimatter wave by the Anti-Monitor on December 10, 2019. It is unknown if she was restored after the Paragons and the Spectre created a new universe, but it is known that Philippe was never married to her on Earth-Prime.
When Philippe discovered the existence of Amélie and Luca, Philippe decided to get revenge on the Flash, in particular, and Earth-Prime, in general, by destroying the new world; the Flash was able to dissuade him though. Amélie could be alive and well in the new multiverse, having just not met Philippe and started a family with him.