The Loop (TV)
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- For the eponymous character, see Jefferson Pierce.
- For the similarly-titled episode, see "".
|Black Lightning is recruited to rally against The 100 gang. Anissa investigates the new drug hitting the streets. Meanwhile, familiar faces begin to reappear.|
- Cress Williams as Jefferson Pierce/Black Lightning
- China Anne McClain as Jennifer Pierce
- Nafessa Williams as Anissa Pierce
- Christine Adams as Dr. Lynn Stewart
- Marvin "Krondon" Jones III as Tobias Whale
- Damon Gupton as Inspector Bill Henderson
- James Remar as Peter Gambi
- Jill Scott as Lady Eve
- Jordan Calloway as Khalil Payne
- Skye P. Marshall as Kara Fowdy
- Edwina Findley as Tori
- Jason Louder as Two-Bits
- Chantal Thuy as Grace Choi
- Amanda Davis as Joan Lincoln
- Al-Jaleel Knox as LaShawn
- Kat Logan as Neema
- Eric Mendenhall as Joey Toledo
- Taylor Polidore as Lisa
- Karen Ceesay as Veretta
- Michael King as Bernard
- Derrick LeMont as Mr. Lewis
- Estes Tarver as Leonard
- Jennifer Van Horn as Rose
- Michael Finn as Man
- Darone Okolie as Bam
- Alex Phipps as Block
- Yolanda T. Ross as Khalil's Mother
- Scarlet Olivia Dunbar as Student #2
- Derrion Elmore as Student #1
- Jennifer Martin as Nurse #2
- Aaron Nelson as Security Officer
- Chan Ta Rivers as Nurse #1
- The episode was previously titled "Jagged Little Pill".
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