After the S.T.A.R. Labs particle accelerator exploded, Eobard acted crippled and began using the wheelchair. He used it to eliminate any consideration of him being the Reverse-Flash and for sympathy, as well as to charge his super speed.
After Eobard was erased from existence when his ancestor Eddie killed himself, the team stowed away the wheelchair. The parts used to charge Thawne's speed were used as parts to the Power Cane, a device employed to stabilize the condition of Martin Stein during the search for a second Firestorm.
After Zoom damaged Barry's spine, he used the wheelchair until he could walk again.
During Earth X's New Reich's attempt to invade Earth-One, Thawne briefly used the wheelchair, mainly due to his sentiment that he had built S.T.A.R. Labs and ran it for 15 years.
The wheelchair was later used by Harrison Sherloque Wells to determine Nora West-Allen's motive for time-traveling to 2018, suspecting that it had something to do with Eobard. He later discovered a flash drive within the wheelchair containing Eobard's personal notes, one of them on the nature of timelines and their malleability.
- Eobard Thawne (stopped using it after his true identity was discovered)
- Barry Allen (after Zoom damaged Barry's spine, Barry used the wheelchair until he could walk again)
- Harrison Sherloque Wells (used to put himself in the mental space of Eobard Thawne in his investigation of Nora West-Allen)
The Flash: Season Zero
- Eobard prepared to get out of it distinctively twice when he was still using it, once when he almost stepped out of it to save Barry, and a second time when he almost sped out of it when a robotic bee almost stung him.