An unfortunate incident in downtown Gotham alerts Batwoman and the Bat Team that another missing trophy has made its way into the wrong hands. Meanwhile, a new member of the Jet family surfaces when Marquis Jet makes a not-so-subtle entrance, interrupting a very personal moment between Ryan and Jada. Back on the streets, cryogenics is the name of the game and Sophie reminds everyone she's a badass, especially in the middle of life-threatening situations. Batwing must decide if he's ready to suit up again, and at Mary's clinic, the Hippocratic Oath forces a strained sisterly moment between Alice and the new doc.[src]
Despite their antagonism, Nora Fries recognizes that Beth and Mary certainly fight like sisters.
McGregor's Disease is the same fictional affliction that Nora Fries suffered from in the film Batman and Robin (1997). It has also previously appeared in the Arrowverse, with William Tockman/Clock King also suffering from it and Francine West dying from it on the first half of Flash Season 2.
As of this episode, Ryan Wilder has officially been the lead character for more episodes than Kate Kane.