The Flash makes an appearance in National City and signs autographs with Supergirl to the delight of the citizens, after they deal with Weather Witch.[2]
During the Worldwide Unity Festival, the Superfriends fight Jarhanpurians but the immortals disappear mid-battle.[8]
Kate Kane took a flight to National City in order to ask Kara if she could destroy the fragment of Kryptonite Kate was holding for her. Though Kate told the Bat Team that she was returning to Gotham City in the morning, the weather of National City caused the flight to delay until the night.[9] Months later, Julia Pennyworth called an attendant who told her that it was his second time conversing with her about what had happened to Kate.[10]
The Superfriends fought valiantly to keep a Phantom Zonephantom dubbed "Prime Phantom" from transforming the residents of the city because, if left unchecked, it would have contaminated the world.[11]
The addresses for victims of the Phantom attack give zip codes which relate to locations in and surrounding San Francisco, indicating National City is located in the location of real-world San Francisco.
However, it has previously been confirmed that San Francisco exists on Earth-Prime, and so it is unlikely National City would be located exactly here (if in California).
As Los Angeles is now on Earth-Prime, it is also unlikely that National City would be placed here.
A very far view of National City, CA.
Coincidentially, there exists a real-life National City, California. However, this National City is far more developed than what exists in reality; exterior shots typically use Los Angeles as the backdrop as was done on Earth-38.
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