nexus is a place located between the multiverse and the netherverse. It was used to store the antimatter cannon until the cannon's destruction.
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In late 2018,
Mar Novu accidentally sent Barry Allen of Earth-90 to the netherverse. He was later found by Mobius who put him in the nexus and forced him to run on a treadmill to power up the antimatter cannon.
In late 2019,
Mobius sensed the existence of Mar Novu on Earth-2 and went to the nexus to turn on the antimatter cannon, test firing it.
Harrison Nash Wells detected antimatter under Central City and began his search for methods to open the door to the nexus. He set up a worksite in order to open the door.
On December 9, 2019 at 11:58pm, Nash talked to Mobius, thinking he was Mar Novu. He later pressed buttons on the door and he was sucked into the nexus, becoming Pariah.
  
On December 10, 2019,
Barry Allen of Earth-1, Caitlin Snow and Cisco Ramon arrived at the door to the nexus. However, they didn't know how to open it, until Cisco vibed Nash and opened the door. They soon realized that Earth-90 Barry was forcibly charging the antimatter cannon.
DC's Legends of Tomorrow