- "Why would you hide from me, now that you have seen what you can be, the power you can have?"
- "I don't want it. You're nothing but a cancer. I know you think you're gonna escape and take control. But my friend and I are gonna stop you."
- —Reign and Samantha Arias
|Supergirl and Imra have different ideas on how to stop the third Worldkiller, Pestilence. However, when both Alex and Winn are seriously injured by Pestilence, Supergirl and Imra team up to stop the destruction.|
- Melissa Benoist as Kara Danvers/Supergirl
- Mehcad Brooks as James Olsen
- Chyler Leigh as Dr. Alex Danvers
- Jeremy Jordan as Winn Schott
- Katie McGrath as Lena Luthor
- Odette Annable as Samantha Arias/Reign
- Chris Wood as Mon-El
- David Harewood as Director J'onn J'onzz
- Jesse Rath as Querl Dox/Brainiac 5
- Amy Jackson as Imra Ardeen/Saturn Girl
- Krys Marshall as Julia Freeman/Purity
- Angela Zhou as Dr. Grace Parker/Pestilence
- Taylor Hastings as Adelaide
- Fred Henderson as Mayor of Sims
- Laurie Murdoch as CEO
- Daesha Usman as Clerk
- Kelly Ann Woods as Chief of Staff
"Of Two Minds" begins with a lady giving out treats at a National City bank. In the wake of eating one of the treats, blood begins spilling out of the nose of an investor.
Kara, Mon-El, Imra, and Alex are looking at one of the dead pigeons from the finish of a week ago's scene. Alex uncovers that the winged animals didn't move sickness between one another. Or maybe, the flying creatures came and direct contact with Pestilence.
An obscure man strolls into the DEO lab, and the group arms their weapons. We rapidly discover that the man is Brainiac-5 utilizing a picture inducer after he created an uproar with his genuine ganders at a neighborhood Piggly Wiggly.
Winn strolls in and tells the gathering of the circumstance at the bank, where a few people are wiped out with fevers and ridiculous noses.
Lena is as yet working with Sam on evaluating how to fix her condition. Lena begins running Sam through more tests, one in which Lena is apparently moved to another measurement where she's compelled to battle her adjust personality Reign.
Group Supergirl shows up at the bank and starts their examination. As they start posing inquiries, the gathering is occupied by an uproar outside. They run outside to discover the Imra has put a power field around the bank, causing widespread panic by individuals downtown.
Imra's attempting to disconnect the bank from the remainder of the city, however Kara's ready to persuade Imra to bring the power field down so they can ship patients to region emergency clinics.
Sam awakens back and reveals to Lena that she had visited an equal measurement, where she conversed with Reign.
Mon-El and Imra talk about the strain among her and Kara. Mon-El notices to his better half that possibly Kara is directly about Pestilence.
Somewhere else, Alex has a go at persuading Kara to work with Imra on this Pestilence issue. Winn runs in with data that the woman distributing treats at the bank prior has kicked the bucket. Believing she's Pestilence, Kara hurries to the scene just to discover Imra remaining over the dead body.
Back at the DEO, Winn discloses to Alex how he was certain the treat woman was Pestilence and as he's talking, Alex sees Winn's nose begin to drain.
The group rendezvous back at the DEO to perceive how Winn is getting along, who's vigorously quieted by painkillers. Winn doesn't remember who scratched his hand contaminating him.
Kara sees Imra stroll by and stands up to her about denouncing any and all authority. Imra clarifies how horrid what's to come is, referencing that Kara neglects to stop Pestilence
Sam's back in the pocket measurement addressing Reign. Rule takes a stab at persuading Sam to give up her life however Sam rapidly awakens.
J'onn and Kara are discussing their fight with Pestilence. Kara inquires as to whether he thinks they'll have the option to bring down Pestilence, and the martian gives her a speedy persuasive talk.
Imra and Mon-El are discussing Kara on the boat. Mon-El discovers that Imra didn't disclose to Kara the entire anecdote regarding why the Legion truly returned. The couple contends and IMra stomps off. Brainiac-5 strolls in and advises something has happened to Winn.
Back at the DEO, Winn is seizing. Brainiac-5 uncovers that the fix they recently utilized on Winn is an inappropriate recipe and for the equation to work, they'll need Pestilence's DNA. Alex breakdown and it's uncovered she's been tainted also.
James strolls in to converse with Winn and the two offer a genuine talk where Winn concedes he's hesitant to bite the dust.
James calls Lena and requests that her work on a pharmaceutical for the tainted and acting ignorant to not let on she's working with Sam, she says she's as of now taking a shot at a medication for it.
Sam returns into the pocket measurement to defy Reign. The two battle and after Reign says she's going to slaughter Ruby, Sam awakens directly back. Sam asks Lena to go to the DEO or Supergirl for more assistance however Lena can't. Lena vows to ensure Ruby and not let anything happen to her.
Kara, Mon-El, J'onn, and Brainiac-5 are as yet taking a shot at the instance of the debilitated individuals. Utilizing online networking, they discover that the specialist the gathering conversed with before in the scene each associated with Dr. Beauty Parker, and the gathering arrives at the resolution that she is Pestilence. As Kara, J'onn, and Mon-El leave to find Parker, Brainiac-5 raidos to Imra disclosing to her they found the character of Pestilence.
We see Dr. Parker enter a meeting room as she's holding a baffling gleaming vial. As Dr. Parker is going to assault one of the board individuals, Kara and Mon-El show up and the previous starts conversing with Dr. Parker. Dr. Parker doesn't tune in and starts battling with the three metahumans.
Kara and Dr. Parker are battling when Imra exemplifies Parker/Pestilence in a power field. Imra tosses a dart at Pestilence in order to kill her, however Purity — the second Worldkiller — appears at salvage her.
At first annoyed, Imra is diminished the discover that Pestilence deserted the dart, giving the group enough DNA for Brainiac-5 to change the fix.
Alex and Winn both get the new fix. J'onn notices to Alex that he didn't know whether he'd have the option to overcome the stuff with his dad without her and the two grasp.
Kara approaches Imra, attempting to improve her vibe about their bombed battle before. Imra uncovers that her sister dies later on from Pestilence's scourge. Kara says they'll battle Pestilence together.
Brainiac-5 and Winn uncover they're presently ready to follow Pestilence's warmth signature and ready beginnings going off — Purity and Pestilence have found Sam/Reign to Lena's safehouse.
Kara, J'onn, Imra and Mon-El go to Lena's area and are to stunned to discover Lena has been working with Sam, the third Worldkiller. When Purity and Pestilence show up at the area, Sam transforms into Reign and the three Worldkiller's fly away.
- The title refers to Supergirl and the the team finding out that Samantha and Reign are the same person.
- When Brainy attempts to figure out who scratched Winn, Winn begins describing Freddy Krueger, the main antagonist of the Nightmare on Elm Street franchise, which Kara and Alex quickly catch on to.
- When J'onn tells Kara that she simply has to try, she tells him that that isn't what Yoda, a character from the Star Wars franchise, would say. J'onn subsequently quotes Yoda, "do or do not", from the 1980 film The Empire Strikes Back.
- In this episode, it is shown that Reign's suit supposedly materializes out of nowhere, contrary to previous episodes where Samantha was shown to have worn it underneath her clothes.
- When she's united with Purity and Pestilence, Reign chants, "El mayarah". The phrase has previously been mentioned to be Kryptonese for "stronger together", and is what the House of El coat of arms - the "S" Kara wears on her suit - means.
- Grace Parker's "god complex" comment was a possible nod to the 1993 thriller film Malice, in which a doctor gave a similar speech. It also starred Brenda Strong who portrays Lillian Luthor.
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