Mrs. Queller was supposed to pick Ruby Arias up from school due to Samantha Arias' new job schedule. However, Ruby was taken home early by her mother during the day after she physically assaulted a classmate.
As Lena Luthor worked to rid Samantha of Reign, she arranged for Mrs. Queller and Ruby to stay in Lex Luthor's mansion. When Reign escaped and began hunting Ruby, Alex visited to protect her and was welcomed by Mrs. Queller. As they toured through the mansion, Mrs. Queller remarked on the features of the residence, finding its amenities quite lovely once getting over the ownership and decor. Queller then directed Alex to Ruby and was presumably sent home afterwards, not being present for Reign's attack.
- She is apparently a terrible cook.