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- "The world will always need Superman, and when there is a problem, you will be there for them, but right now, this family needs you more."
- —Lois Lane to Clark Kent[src]
|After years of facing megalomaniacal supervillains, monsters wreaking havoc on Metropolis, and alien invaders intent on wiping out the human race, the world's most famous superhero, The Man of Steel aka Clark Kent and comic books' most famous journalist, Lois Lane, come face to face with one of their greatest challenges ever - dealing with all the stress, pressures and complexities that come with being working parents in today's society. Complicating the already daunting job of raising two boys, Clark and Lois must also concern themselves with whether or not their sons Jonathan and Jordan could inherit their father's Kryptonian superpowers as they grow older. Returning to Smallville to handle some Kent family business, Clark and Lois are reacquainted with Lana Lang, a local loan officer who also happens to be Clark's first love, and her Fire Chief husband Kyle Cushing. The adults aren't the only ones rediscovering old friendships in Smallville as the Kent sons are reacquainted with Lana and Kyle's rebellious daughter, Sarah. Of course, there's never a dull moment in the life of a superhero, especially with Lois' father, General Samuel Lane looking for Superman to vanquish a villain or save the day at a moment's notice. Meanwhile, Superman and Lois' return to idyllic Smallville is set to be upended when a mysterious stranger enters their lives.|
- Tyler Hoechlin as Clark Kent/Superman
- Elizabeth Tulloch as Lois Lane
- Jordan Elsass as Jonathan Kent
- Alex Garfin as Jordan Kent
- Erik Valdez as Kyle Cushing
- Inde Navarrette as Sarah Cushing
- Wolé Parks as John Henry Irons
- Adam Rayner as Tal-Rho/Morgan Edge
- Dylan Walsh as Sam Lane
- Emmanuelle Chriqui as Lana Lang Cushing
- Sofia Hasmik as Chrissy Beppo (season 2; recurring season 1)
- Superman & Lois is an indirect reference to the 1993 television series; Lois & Clark: The New Adventures of Superman.
- The unproduced fifth season of Lois & Clark would have been centered on the protagonists raising a child together, which is similar to the Superman & Lois premise.
- Filming for season one began on October 21, 2020. 
- There was going to be a crossover episode with the second season of .
- However, on January 14, 2021, it was announced that the crossover was cancelled due to the COVID-19 pandemic.
- On March 2nd, 2021, Superman and Lois was renewed for a second season by the CW.
- 'Walker' & 'Superman & Lois' Get Additional Episodes At the CW - Deadline
- "'Superman & Lois' Renewed For Season 2 By the CW" - Deadline
- "‘Superman & Lois’: Sofia Hasmik Upped To Series Regular For Season 2" - Deadline
- "Superman & Lois Star Elizabeth Tulloch Signals Filming Start" - Bleeding Cool
- "The CW Plots ‘Superman’ & ‘Batwoman’ Crossover In 2021" - Deadline
- "Batwoman's Javicia Leslie Wants a 'Super Black' Arrowverse Crossover" - TVLine
|Superman & Lois|
|Superman & Lois: Season 1 • Season 2|
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|Comic book series|
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|• Novels • Shorts • Movies • Specials • • • •|
|Batman '66 universe • DC Extended Universe • Doom Patrol universe • Lucifer universe • Smallville universe • Stargirl universe • Superman Anthology universe • Batman Anthology universe • Swamp Thing universe • Titans universe • Wonder Woman universe|