- "My name Is Iris West-Allen and I once met a young man, a superhero who I called the Streak. The world has come to know him as the Fastest Man Alive, the Scarlet Speedster, the Flash. But no matter what title you choose for him, he'll always be remembered as the protector of our amazing city and it's citizens, as a beacon of hope for us all, and as the man who sacrificed himself again and again so we could live. Today we say goodbye to him. Today we say goodbye to him, not because he was taken but because he gave himself willingly. And in the end, that's what makes him deserving of the greatest title of all. Hero."
- —Iris West-Allen on the Flash's death
It will act as the first half of a two-part episode.
As Barry Allen stands on the threshold of his impending death in Crisis, his convictions are tested when the monstrous Dr. Ramsey Rosso infects the Flash with a mysterious, hallucinogenic contagion. Meanwhile, reporter Iris West-Allen uncovers a vast conspiracy.
- This episode is the first time Ramsey is called "Bloodwork".
- The title is a reference to the film The Last Temptation of Christ.
- This episode can be compared to the episode "" in that in both episodes, an antagonist possesses the male lead while he is saving a teammate. In the latter, Ray Palmer allows himself to be possessed by Neron in order to stop him from killing Nate Heywood, while in this episode, Ramsey infects Barry while he is donating blood to Ralph.
- Iris starts to write a version of the article covering Flash's disappearance in the Crisis of 2019 seen since "".
- As of this scene, Iris is the show's third character to have a "My name is" monologue after Barry and Nora West-Allen.
- When Barry is infected by Ramsey, his appearance and lightning color are based on that of the Negative Flash from the comics, wherein Barry was similarly infected but rather by Thawne with the Negative Speed Force.
- Allegra mentions that there are 2 days until Crisis, implying that this episode takes place on December 8, 2019. This may be a reference to the fact that this episode is also 2 episodes before .
- This is the first episode of that is not a part of a crossover to end with "To Be Continued".
- This is the second official first half of a two-part episode of a television series in the Arrowverse, after the episode ""
- At one point in his coma, Barry finds himself walking among the gravestones of everyone he failed to save and stops before his own grave. This is a reference to Ebenezer Scrooge in the famous novella A Christmas Carol.
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